USADA Funded Research
During the period from (2001-2009), USADA budgeted $2 million per year to support research related to the deterrence of the use of performance-enhancing drugs in sport. The broad range of anti-doping research activities previously undertaken by USADA have been assumed by the Partnership for Clean Competition. USADA still considers funding research projects that have been presented to the PCC (or WADA) first based on the guidelines from the USADA Research Priorities Policy. In the section below, you can find detailed information about past USADA-funded research and its impact on anti-doping science.
Detection of exogenous growth hormone, its analogs, mimetics, and secretagogues
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| Center of Excellence Instrumentation Grants | 8/1/2007 – 8/30/2007 | Doug Rollins MD, PhD | SMRTL |
| Center of Excellence Instrumentation Grants | 3/24/2006 – 12/31/2009 | USADA Equipment on lease to Don Catlin MD | Anti-Doping Research Institute, Inc. |
| Displacement of growth hormone secretagogues – out of the receptor and out of the pitch- | 1/15/2006 – 12/31/2008 | Jordi Segura PhD | Institut Muncipial D’Investigacio Medica |
| Development of an immunoassay for a novel serum biomarker of GH administration | 1/1/2006 – 12/31/2006 | Robert Baxter PhD | University of Sydney |
| The Development of a methodology for detecting abuse with Growth Hormone in Sport: GH-2004-Pilot study on Ethnic Effects | 1/1/2003 – 8/1/2006 | Richard Holt MD | University of Southampton |
| Development and Clinical Validation of Sandwich Immunoassays for the Quantitation of Insulin-Like Growth Factor 1 and the N-Terminal Propeptide of Type III Collagen in Human Serum | 8/1/2002 – 10/25/2004 | Donald Very PhD | The Institute of Bioanalytics |
Detection of O2 transport-enhancing substances and methods
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| Detection of autologous blood transfusion via analysis of peripheral blood samples | 12/30/2006 – 12/30/2007 | Michael Ashenden PhD | Science and Industry Against Blood Doping (SIAB) |
| Validation and implementation of a test for a recent autologous blood transfusion | 11/15/2006 – 11/16/2008 | Ross Brown PhD | Royal Prince Alfred Hospital |
| Red Blood Cell Marker MoAbs for Flow Cytometry | 4/1/2006 – 4/1/2009 | Bruce Davis | Trillium Diagnostics, LLC |
| Center of Excellence Instrumentation Grants | 3/23/2006 – 9/18/2008 | Diana Wilkins, PhD, Doug Rollins, MD, PhD | SMRTL |
| Determining blood-doping-associated neocytolysis by flow cytometry- a novel method to detect blood-doping by athletes | 1/1/2006 – 12/31/2007 | Chung-Che Chang MD, PhD | The Methodist Hospital Research Institute |
| Development of a test to detect a recent autologous transfusion | 6/1/2005 – 5/31/2006 | Ross Brown PhD | Royal Prince Alfred Hospital |
| Characterisation of gene expression profiles associated with the use of erythropoietic stimulants | 11/15/2004 – 11/15/2004 | Michael Ashenden PhD | Science and Industry Against Blood Doping (SIAB) |
| A Novel Method for the Detection of Exogenous Erythropoietin in Human Urine | 7/1/2004 – 1/1/2006 | Richard Zare PhD | Stanford University |
| Development of a Test or Tests to Deter the Abuse of Autologous Blood Transfusion in Sport | 11/1/2003 – 11/1/2004 | Margaret Nelson PhD | Institute of Haematology, Royal Prince Alfred Hospital |
| Improving the Detection of Erythropoietin Administration | 3/1/2003 – 3/1/2004 | Don Catlin MD | University of California, Los Angeles |
| Development of a test or tests to deter the abuse of blood transfusion in sport | 11/1/2002 – 11/14/2003 | Margaret Nelson PhD | Institute of Haematology, Royal Prince Alfred Hospital |
| Development, application, and characterization of an index for detecting erythropoietin administration | 7/1/2000 – 6/30/2003 | Don Catlin MD | University of California, Los Angeles |
Detection of synthetic anabolic steroids
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| The synthesis and certification of 2E-hydroxymethylethisterone reference material for the detection and quantitative measurement of danazol | 10/1/2006 – 3/31/2007 | Laurie Besley PhD | National Measurement Institute of Australia |
| Studies of norandrosterone in women | 9/1/2005 – 8/31/2008 | Andrew Kicman PhD | King’s College London |
| Deuterated 19-Norandrosterone glucuronide reference material | 8/15/2005 – 12/1/2005 | Laurie Besley, Besley PhD | National Measurement Institute of Australia |
| Identification and Production of Metabolites of Mibolerone | 12/8/2004 – 5/15/2005 | Yuri Khmelnitsky PhD | Albany Molecular Research Inc. |
| Human Urinary Steroid profiles after Exposure to Non-Physiologic Steroids and Prohormones Found in Dietary Supplements | 11/1/2004 – 11/25/2006 | Diana Wilkins PhD | University of Utah |
| Preparation of Certified Reference Materials for use in doping analysis for steroid prohormones & 19 nor steroids | 8/4/2003 – 8/30/2003 | Steven Westwood | National Analytical Reference Laboratory |
| Adolescents & Hormone Abuse | 6/14/2002 – 6/14/2003 | Lisa Fish MD | The Hormone Foundation |
| Analysis of 1-AD, and its Metabolites, and Relevant Endogenous Hormones by Mass Spectrometry | 4/1/2002 – 3/31/2003 | Christopher Reilly PhD | University of Utah |
Doping with Genetic Technology
| Detection of Gene Doping after Intramuscular Injection of recombinant Adeno-Associated Viral Vectors | 9/1/2008 – 8/31/2010 | Richard Snyder Ph.D. | University of Florida |
| Ethics, Genetics, and the Future of Sport: The implications of Genetic Modification and Genetic Selection | 6/1/2005 – 5/31/2008 | Thomas Murray PhD | The Hastings Center |
| Gene Expression and Proteomic Effects of IGF-1 in the Mouse | 12/29/2003 – 12/29/2006 | Theodore Friedmann MD | University of California, San Diego |
ETHICAL CONSIDERATIONS
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| Ethical, conceptual, and scientific issues in the use of performance enhancing technologies | 1/1/2002 – 3/14/2005 | Thomas Murray PhD | The Hastings Center |
Improved detection of naturally occurring compounds
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| Center of Excellence Instrumentation Grants | 3/23/2006 – 5/15/2007 | Diana Wilkins PhD | SMRTL |
| Standardization and Methodology for Steroid Isotopic Analysis | 2/15/2006 – 3/31/2009 | James Brenna PhD | Cornell University |
| Improving Urine Testing for Endogenous Steroids by Isotope Ratio Mass Spectrometry | 3/1/2003 – 2/28/2005 | Don Catlin MD | University of California, Los Angeles |
OTHER
| Title | Dates of Grant Funding | Principal Investigator | Institution |
|---|---|---|---|
| Production of 6-Hydroxybromantan Metabolite | 12/15/2004 – 2/15/2005 | Günter Gmeiner PhD | ARC Seibersdorf Research GmbH |
| Synthesis and characterization of the main metabolite of finasteride | 12/15/2004 – 3/1/2006 | Günter Gmeiner PhD | ARC Seibersdorf Research GmbH |
| Synthesis and characterization of a letrozole metabolite | 1/15/2006 – 4/3/2006 | Günter Gmeiner PhD | ARC Seibersdorf Research GmbH |
| Synthesis and characterization of a clomiphene metabolite | 2/1/2007 – 7/15/2008 | Günter Gmeiner PhD | ARC Seibersdorf Research GmbH |
| Provide a database of sources for reference materials for prohibited substances | 2/1/2005 – 8/16/2005 | Laurie Besley PhD | National Measurement Institute of Australia |
| Synthesis and characterization of a tamoxifen metabolite | 2/1/2007 – 7/31/2007 | Günter Gmeiner PhD | ARC Seibersdorf Research GmbH |
| Certification of a reference material for the detection and quantitative measurement of letrazole metabolite | 4/1/2006 – 8/14/2006 | Laurie Besley PhD | National Measurement Institute of Australia |
| Certification of a reference material for the detection and quantitative measurement of finasteride metabolite (carboxylic acid) | 4/1/2006 – 12/31/2007 | Laurie Besley PhD | National Measurement Institute of Australia |
| Certification of a reference material for the detection and quantitative measurement of tamoxifen | 9/1/2007 – 12/1/2007 | Laurie Besley PhD | National Measurement Institute of Australia |
| Certification of 6-hydroxy-bromantan reference material | 5/15/2005 – 8/17/2005 | Laurie Besley PhD | National Measurement Institute of Australia |
Learn more about USADA’s Scientific Research.